Product Details
Cefoperazone Injection powder for solution
1g/2g
Product Description :
CEFOPERAZONE INJECTION 1 g / 2 g
Sterile Powder for Solution for Intravenous or Intramuscular Administration
1. COMPOSITION
Each vial contains:
• Cefoperazone Sodium equivalent to Cefoperazone 1 g / 2 g.
• Excipients: As applicable.
2. PHARMACEUTICAL FORM
Sterile, white to off-white powder for solution for intravenous or intramuscular administration.
3. THERAPEUTIC CLASS
Third-Generation Cephalosporin Antibiotic.
4. INDICATIONS
Cefoperazone Injection is indicated for the treatment of susceptible bacterial infections, including:
• Lower respiratory tract infections.
• Urinary tract infections.
• Intra-abdominal infections.
• Biliary tract infections.
• Skin and soft-tissue infections.
• Bone and joint infections.
• Gynecological and pelvic infections.
• Septicemia and other serious bacterial infections.
Treatment should be guided by the susceptibility of the causative organism and applicable antimicrobial guidelines.
5. CONTRAINDICATIONS
• Hypersensitivity to cefoperazone, cephalosporins, or any component of the formulation.
• History of severe immediate hypersensitivity reactions to beta-lactam antibiotics.
6. DRUG INTERACTIONS
• Alcohol-containing beverages or preparations may cause a disulfiram-like reaction with cefoperazone.
• Anticoagulants may increase the risk of bleeding and may require appropriate monitoring.
• Concomitant nephrotoxic medicines may increase the risk of renal toxicity.
• Probenecid may affect renal elimination of cefoperazone.
The treating physician should review all concomitant medications before administration.
7. ADMINISTRATION
For intravenous or intramuscular administration after reconstitution with a compatible diluent under aseptic conditions. Administer according to the approved product information and institutional protocol.
8. STORAGE
Store according to the storage conditions stated on the approved product label. Protect from excessive heat, moisture and light. After reconstitution, use within the period specified in the approved product information. Do not use if the reconstituted solution shows visible particles, precipitation or unexpected discoloration.