Product Details
Ceftriaxone Sodium + Tazobactum Injection Usp
250MG+31.25MG / 1GM+125MG / 2GM+250MG
Product Description :
CEFTRIAXONE SODIUM + TAZOBACTAM INJECTION USP
250 mg + 31.25 mg / 1 g + 125 mg / 2 g + 250 mg
Sterile Powder for Solution for Intravenous or Intramuscular Administration
COMPOSITION
Each vial contains:
Ceftriaxone Sodium equivalent to Ceftriaxone ............... 250 mg
Tazobactam Sodium equivalent to Tazobactam ............... 31.25 mg
or
Ceftriaxone Sodium equivalent to Ceftriaxone ............... 1 g
Tazobactam Sodium equivalent to Tazobactam ............... 125 mg
or
Ceftriaxone Sodium equivalent to Ceftriaxone ............... 2 g
Tazobactam Sodium equivalent to Tazobactam ............... 250 mg
Excipients: As applicable.
PHARMACEUTICAL FORM
Sterile, white to yellowish powder for solution for intravenous or intramuscular administration.
THERAPEUTIC CLASS
Third-Generation Cephalosporin Antibiotic + β-Lactamase Inhibitor
INDICATIONS
Ceftriaxone Sodium + Tazobactam Injection is indicated for the treatment of moderate to severe bacterial infections caused by susceptible microorganisms.
It may be used in the treatment of:
• Lower respiratory tract infections
• Complicated urinary tract infections
• Intra-abdominal infections
• Skin and soft-tissue infections
• Bone and joint infections
• Septicemia and bloodstream infections
• Bacterial meningitis
• Infections of the biliary tract
• Gynecological infections
• Other serious infections caused by susceptible bacteria
Treatment should be guided by the susceptibility of the causative organism and applicable antimicrobial guidelines.
CONTRAINDICATIONS
Ceftriaxone Sodium + Tazobactam is contraindicated in patients with known hypersensitivity to ceftriaxone, tazobactam, other cephalosporins, penicillins, or any component of the formulation.
DRUG INTERACTIONS
Particular consideration may be required with concomitant use of:
• Calcium-containing intravenous solutions
• Anticoagulants such as warfarin
• Aminoglycoside antibiotics
• Other nephrotoxic medicines
• Other β-lactam antibiotics
The treating physician should review all concomitant medications before administration.
ADMINISTRATION
Ceftriaxone Sodium + Tazobactam Injection may be administered by intravenous or intramuscular route according to the approved product information.
The contents of the vial should be reconstituted with a suitable compatible diluent under appropriate aseptic conditions.
For intravenous administration, the reconstituted solution should be further diluted as required and administered by a qualified healthcare professional according to the approved product information and institutional protocol.
For Intravenous or Intramuscular Use Only.
STORAGE
Store according to the storage conditions stated on the approved product label.
Protect from excessive heat, moisture and light.
After reconstitution/dilution, use within the period specified in the approved product information.
Do not use if the reconstituted solution shows visible particles, precipitation or unexpected discoloration.