Product Details
Chloramphenicol sodium succinate injection
1GM
Product Description :
CHLORAMPHENICOL SODIUM SUCCINATE INJECTION 1 g
Sterile Powder for Solution for Intravenous Administration
COMPOSITION
Each vial contains:
Chloramphenicol Sodium Succinate equivalent to Chloramphenicol ............... 1 g
Excipients: As applicable.
PHARMACEUTICAL FORM
Sterile, white to off-white powder for solution for intravenous administration.
THERAPEUTIC CLASS
Amphenicol Antibiotic
INDICATIONS
Chloramphenicol Sodium Succinate Injection is indicated for the treatment of serious infections caused by susceptible microorganisms when less hazardous antimicrobial agents are ineffective or contraindicated.
It may be used in the treatment of:
• Typhoid fever and other serious Salmonella infections
• Meningitis caused by susceptible organisms
• Rickettsial infections when appropriate alternatives are unsuitable
• Serious anaerobic infections caused by susceptible organisms
• Other serious bacterial infections when clinically justified
Treatment should be guided by the susceptibility of the causative organism and applicable antimicrobial guidelines.
CONTRAINDICATIONS
Chloramphenicol is contraindicated in patients with:
• Known hypersensitivity to chloramphenicol or any component of the formulation
• Previous history of serious blood dyscrasias or bone-marrow depression associated with chloramphenicol
• Minor infections or conditions for which safer effective alternatives are available
DRUG INTERACTIONS
Particular consideration may be required with concomitant use of:
• Anticoagulants such as warfarin
• Phenytoin
• Phenobarbital
• Other medicines that may suppress bone marrow function
• Other medicines metabolized through hepatic enzyme systems
The treating physician should review all concomitant medications before administration.
ADMINISTRATION
Chloramphenicol Sodium Succinate Injection is intended for intravenous administration.
The contents of the vial should be reconstituted with a suitable compatible diluent under appropriate aseptic conditions.
The reconstituted solution should be administered by a qualified healthcare professional according to the approved product information and institutional protocol.
For Intravenous Use Only.
STORAGE
Store according to the storage conditions stated on the approved product label.
Protect from excessive heat, moisture and light.
After reconstitution, use within the period specified in the approved product information.
Do not use if the reconstituted solution shows visible particles, precipitation or unexpected discoloration.