Product Details
Acyclovir sodium for injection
250MG/500MG
Product Description :
ACYCLOVIR SODIUM FOR INJECTION 250 mg / 500 mg
Sterile Powder for Solution for Intravenous Administration
1. COMPOSITION
Each vial contains:
• Acyclovir Sodium equivalent to Acyclovir 250 mg / 500 mg.
• Excipients: As applicable.
2. PHARMACEUTICAL FORM
Sterile, white to off-white powder for solution for intravenous administration.
3. THERAPEUTIC CLASS
Antiviral Agent – Nucleoside Analogue.
4. INDICATIONS
Acyclovir Sodium for Injection is indicated for the treatment of serious infections caused by Herpes simplex virus (HSV) and Varicella-zoster virus (VZV), including:
• Herpes simplex encephalitis.
• Severe or disseminated Herpes simplex infections.
• Severe Varicella-zoster infections.
• Herpes zoster infections in immunocompromised patients.
• Other serious HSV/VZV infections requiring intravenous antiviral therapy.
Treatment should be guided by the clinical condition and applicable antiviral guidelines.
5. CONTRAINDICATIONS
• Hypersensitivity to acyclovir, valacyclovir, or any component of the formulation.
• Use should be carefully evaluated in patients with significant renal impairment.
6. DRUG INTERACTIONS
• Concomitant nephrotoxic medicines may increase the risk of renal toxicity.
• Probenecid may reduce renal elimination of acyclovir and increase exposure.
• Mycophenolate mofetil may increase acyclovir exposure.
• Other medicines affecting renal function should be used with caution.
The treating physician should review all concomitant medications before administration.
7. ADMINISTRATION
For intravenous administration only. Reconstitute and dilute with a compatible diluent under aseptic conditions and administer by slow intravenous infusion according to the approved product information and institutional protocol.
8. STORAGE
Store according to the storage conditions stated on the approved product label. Protect from excessive heat, moisture and light.